Identifying cross-tissue molecular targets of lung function by multi-omics integration analysis from DNA methylation and gene expression of diverse human tissues
This study identified potential cross-tissue molecular targets associated with lung function traits from DNA methylation and gene expression of diverse tissues and explored the probable regulation mechanism of these molecular targets. This provides multi-omics and cross-tissue evidence for the molecular regulation mechanism of lung function and may provide new insight into the influence of crosstalk between organs and tissues on lung function.
Authors
- Senquan Wu
- Sichong Peng (ORCID: https://orcid.org/0000-0003-3400-298X)
- Weiliang Mo
- Jiayi Fang
- Guodong Hu
Institutions
- Dongguan People’s Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1186/s12864-025-11476-2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00