Bupleuri Radix Ameliorates Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Modulation of Tight Junction Protein Expression and Inhibition of Nuclear Factor-κB Activation
These findings revealed for the first time that BR prevents IL-1β-induced inflammation of blood vessel. Therefore, BR has the potential to protect the damage of vascular endothelial cells and prevent the progression of cardiovascular diseases.
Authors
- EunJin Bang (ORCID: https://orcid.org/0000-0003-3847-4992)
- Min Yeong Kim (ORCID: https://orcid.org/0000-0001-9083-8218)
- Su Hyun Hong (ORCID: https://orcid.org/0000-0001-9291-5803)
- Yung Hyun Choi (ORCID: https://orcid.org/0000-0002-1454-3124)
Institutions
- Dong-Eui University (KR)
Publication Details
- Journal
- Journal of pharmacopuncture
- Published
- 2025-03-24
- DOI
- https://doi.org/10.3831/kpi.2025.28.1.57
- Citations
- 1
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea