How is single-cell RNA sequencing contributing to the advancement of cancer therapeutics?

The study of Tang <i>et al</i> investigated the distribution and dynamic changes of cell populations in the tumor microenvironment of gastric cancer (GC) patients using single-cell RNA sequencing (scRNA-seq). This comprehensive analysis highlights key interactions within the tumor microenvironment across different GC stages. Discussing applications of scRNA-seq data in clinical settings could pave the way for developing promising and personalized therapeutic strategies for GC patients. Therefore, further exploration of selecting anticancer drug candidates through gene screening derived from scRNA-seq will provide deeper insights into GC care.

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Publication Details

Journal
World Journal of Gastrointestinal Oncology
Published
2025-03-24
DOI
https://doi.org/10.4251/wjgo.v17.i4.103480
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

How is single-cell RNA sequencing contributing to the advancement of cancer therapeutics?

Keun‐Yeong Jeong
World Journal of Gastrointestinal Oncology
Cancer Genomics and Diagnostics
article

How is single-cell RNA sequencing contributing to the advancement of cancer therapeutics?

Keun‐Yeong Jeong
article en

Abstract

The study of Tang <i>et al</i> investigated the distribution and dynamic changes of cell populations in the tumor microenvironment of gastric cancer (GC) patients using single-cell RNA sequencing (scRNA-seq). This comprehensive analysis highlights key interactions within the tumor microenvironment across different GC stages. Discussing applications of scRNA-seq data in clinical settings could pave the way for developing promising and personalized therapeutic strategies for GC patients. Therefore, further exploration of selecting anticancer drug candidates through gene screening derived from scRNA-seq will provide deeper insights into GC care.

World Journal of Gastrointestinal OncologyVol. 17(4)
Naver (South Korea) (KR)
Good health and well-being
Openalex Percentile: Top 93%
Cancer Genomics and Diagnostics
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