β-caryophyllene reduces inflammation to protect against ischemic stroke by suppressing HMGB1 signaling
These data indicate that BCP exerts a protective effect against ischemic stroke-induced inflammatory injury by regulating the HMGB1/TLR4/RAGE signaling pathway, which provides new insights into the mechanisms of this therapeutic candidate for the treatment of ischemic stroke.
Authors
- Jingdong Liu (ORCID: https://orcid.org/0000-0003-3383-061X)
- Daohang Liu (ORCID: https://orcid.org/0000-0001-6547-1258)
- Zhi Dong (ORCID: https://orcid.org/0000-0001-5872-8174)
- Yang Yang (ORCID: https://orcid.org/0000-0003-0428-5480)
- Sha Chen (ORCID: https://orcid.org/0000-0003-0572-9776)
- Yuchun Wang (ORCID: https://orcid.org/0000-0002-8362-5131)
- Shengwei Liu (ORCID: https://orcid.org/0000-0002-2102-3434)
- Bharati Laxman
- Tuo Meng
Institutions
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1186/s10020-025-01171-z
- Citations
- 3
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 3.96
Funders
- Chongqing Science and Technology Commission