Global, regional, and national burden of infective endocarditis from 2010 to 2021 and predictions for the next five years: results from the Global Burden of Disease Study 2021

Over the past decade, the ASPR of IE has been on a gradual increase, while the ASDR and the age-standardized DALY rate have slightly decreased. It is indicated that some progress has been achieved in the global disease management and treatment effectiveness of IE. Based on the increasing prevalence rate and the relatively high mortality rate, the burden of IE globally will still remain a major public health challenge in the future.