Diffusion Imaging Protocol Heterogeneity Biases Ischemic Core Volume, Location, and Clinical Associations in Acute Stroke
Imaging protocol heterogeneity leads to significant changes in the ADC distribution, ischemic core location, size, and association with clinical scores. Work is needed in standardizing imaging protocols to improve the reliability of ADC as an imaging biomarker in stroke management protocols to improve the reliability of ADC as an imaging biomarker in stroke management.
Authors
- Veronica Ravano (ORCID: https://orcid.org/0000-0002-1532-9664)
- Silvia Pistocchi (ORCID: https://orcid.org/0000-0002-5427-4299)
- Guillaume Saliou (ORCID: https://orcid.org/0000-0003-3832-7976)
- Richard McKinley (ORCID: https://orcid.org/0000-0001-8250-6117)
- Jonathan Rafael‐Patiño (ORCID: https://orcid.org/0000-0002-8960-5465)
- Alexander Salerno (ORCID: https://orcid.org/0000-0001-8494-5527)
- Jonas Richiardi (ORCID: https://orcid.org/0000-0002-6975-5634)
- Bénédicte Maréchal (ORCID: https://orcid.org/0000-0001-7866-2854)
- Patrik Michel (ORCID: https://orcid.org/0000-0003-4954-7579)
- Elda Fischi-Gómez (ORCID: https://orcid.org/0000-0002-6506-2128)
- Roland Wiest (ORCID: https://orcid.org/0000-0001-7030-2045)
- Tobias Kober (ORCID: https://orcid.org/0000-0001-7598-9456)
- Antoine Madrona (ORCID: https://orcid.org/0000-0002-8188-4180)
Institutions
- University of Bern (CH)
- Siemens Healthcare (United States) (US)
- École Polytechnique Fédérale de Lausanne (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- Stroke
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1161/strokeaha.124.047317
- Citations
- 3
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Schweizerische Herzstiftung
- Université de Lausanne
- Siemens Healthineers
- Innosuisse - Schweizerische Agentur für Innovationsförderung