Exploring the Challenges of Lipid Nanoparticle Development: The In Vitro–In Vivo Correlation Gap

These findings highlight the complexities of correlating in vitro and in vivo outcomes in LNP development and demonstrate the importance of holistic evaluation strategies to optimise their clinical translation.

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Publication Details

Journal
Vaccines
Published
2025-03-21
DOI
https://doi.org/10.3390/vaccines13040339
Citations
22
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
17.73

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article

Exploring the Challenges of Lipid Nanoparticle Development: The In Vitro–In Vivo Correlation Gap

Yvonne Perrie, Muattaz Hussain, Burcu Binici, Sarah Lindsay
22 citations
Vaccines
RNA Interference and Gene Delivery
17.73
article

Exploring the Challenges of Lipid Nanoparticle Development: The In Vitro–In Vivo Correlation Gap

Yvonne Perrie, Muattaz Hussain, Burcu Binici, Sarah Lindsay
article en
22 citations

Abstract

These findings highlight the complexities of correlating in vitro and in vivo outcomes in LNP development and demonstrate the importance of holistic evaluation strategies to optimise their clinical translation.

VaccinesVol. 13(4)
University of Strathclyde (GB)
Innovate UK
Openalex Percentile: Top 1%
RNA Interference and Gene Delivery
17.73
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Exploring the Challenges of Lipid Nanoparticle Development: The In Vitro–In Vivo Correlation Gap — Yvonne Perrie, Muattaz Hussain, et al. · Vaccines (2025) | TGRS Research Map | TGRS