Transcriptome Sequencing Analysis of the Effects of Metformin on the Regeneration of Planarian Dugesia japonica
The results suggest that metformin accelerates planarian eyespot regeneration, potentially through the regulation of <i>DjCK1α</i>. This study provides the first transcriptome-based analysis of drug effects on regeneration in planarians, highlighting the role of metformin in the regeneration process.
Authors
- Zhu‐An Xu (ORCID: https://orcid.org/0000-0001-9290-2762)
- Kexin Yang (ORCID: https://orcid.org/0000-0003-2333-2406)
- Song Lin-xia (ORCID: https://orcid.org/0000-0002-6515-2895)
- Dandan Yin (ORCID: https://orcid.org/0000-0002-0341-6998)
- Zelong Zhao (ORCID: https://orcid.org/0000-0001-8542-7297)
- Chunmei Zhang (ORCID: https://orcid.org/0000-0003-2381-0498)
Institutions
- Shandong University of Technology (CN)
Publication Details
- Journal
- Genes
- Published
- 2025-03-22
- DOI
- https://doi.org/10.3390/genes16040365
- Citations
- 1
- Primary Topic
- Planarian Biology and Electrostimulation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province