Efficacy of anal botulinum toxin injection in children with functional constipation

Anal BTX injections improved BM frequency with minimal effect on FI with an overall symptom resolution in 21% of patients. BTX does not seem to have a notable effect in patients with FC and developmental delay and/or behavioral disorders. Provider and parental reported success were significantly higher than the actual observed response.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2025-03-24
DOI
https://doi.org/10.1002/jpn3.70040
Citations
5
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
9.06
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article

Efficacy of anal botulinum toxin injection in children with functional constipation

Dhiren Patel, John M. Rosen, Pavithra Saikumar, Leonel Rodriguez et al.
5 citations
Journal of Pediatric Gastroenterology and Nutrition
Gastrointestinal motility and disorders
9.06
article

Efficacy of anal botulinum toxin injection in children with functional constipation

Dhiren Patel, John M. Rosen, Pavithra Saikumar, Leonel Rodriguez, Mayuri Jayaraman, C. M. DESAI
article en
5 citations

Abstract

Anal BTX injections improved BM frequency with minimal effect on FI with an overall symptom resolution in 21% of patients. BTX does not seem to have a notable effect in patients with FC and developmental delay and/or behavioral disorders. Provider and parental reported success were significantly higher than the actual observed response.

Journal of Pediatric Gastroenterology and NutritionVol. 80(6)
Yale New Haven Hospital (US), Cardinal Glennon Children’s Medical Center (US), Children's Mercy Hospital (US), Yale University (US), Cardinal Glennon Children’s Medical Center (US), Saint Louis University (US)
Good health and well-being
Openalex Percentile: Top 2%
Gastrointestinal motility and disorders
9.06
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