Association of Life’s Essential 8 with incidence of heart failure modified by depressive symptoms: a prospective cohort study from UK Biobank
The cohort study revealed that LE8-defined CVH not only could predict the incidence of HF, but also mitigate the increased risk of HF attributable to depressive symptoms. Achieving the high LE8 scores recommended by the AHA to improve CVH will be beneficial in reducing the population burden of HF, especially among patients with depressive symptoms.
Authors
- Jianing Wang (ORCID: https://orcid.org/0000-0001-5752-9050)
- Bao-Peng Liu (ORCID: https://orcid.org/0000-0003-1277-7397)
- Tian Ge (ORCID: https://orcid.org/0000-0003-4785-4444)
- Cun-Xian Jia (ORCID: https://orcid.org/0000-0002-2651-147X)
- Wei Hu (ORCID: https://orcid.org/0000-0002-9107-8027)
- Chunhua Zhao
- Zhenzhen Shen
- Yueqing Huang (ORCID: https://orcid.org/0000-0002-3443-5147)
Institutions
- Shandong University (CN)
- Suzhou Municipal Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1186/s12916-025-04011-3
- Citations
- 3
- Primary Topic
- Cardiovascular Health and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 4.16