Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling
YCHD enhances bile acid metabolism in the liver and promotes bile acid excretion in the kidneys, ameliorating liver damage caused by OJ. These effects are likely mediated by the upregulation of CAR and its nuclear translocation.
Authors
- Hongxia Yuan
- Junjian Liu (ORCID: https://orcid.org/0000-0002-3052-3799)
- Hanwei Mei (ORCID: https://orcid.org/0000-0001-6713-3623)
- Xibo Zhang
- Yanyan Jing (ORCID: https://orcid.org/0009-0001-8013-5188)
- Zhonglian Li (ORCID: https://orcid.org/0000-0002-5125-9851)
- Shu‐Biao Wu (ORCID: https://orcid.org/0000-0002-1790-6015)
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Tianjin Nankai Hospital (CN)
Publication Details
- Journal
- World Journal of Hepatology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.4254/wjh.v17.i3.101724
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00