Blood metabolites mediate causal inference studies on the effect of gut microbiota on the risk of vascular calcification
Gut microbiota and blood metabolites are causally linked to VC. These findings provide a theoretical basis for microbiome- and metabolome-based therapeutic strategies for targeting VC and enhances our comprehension of the gut-vascular axis.
Authors
- Minhong Luo
- Chen Xie (ORCID: https://orcid.org/0000-0003-4738-2117)
- Yang Jin (ORCID: https://orcid.org/0000-0001-5597-8397)
- Sifan Chen (ORCID: https://orcid.org/0000-0001-5264-5650)
- Huijin Zhu
- Hui Huang (ORCID: https://orcid.org/0000-0001-8599-7441)
- Yanli Qi (ORCID: https://orcid.org/0000-0002-8664-8355)
- Aoran Huang
- Li Yin (ORCID: https://orcid.org/0009-0006-5272-7078)
- Mingxuan Zhang (ORCID: https://orcid.org/0000-0003-3324-6675)
- Jianshuai Ma
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1016/j.jare.2025.03.038
- Citations
- 5
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 7.15
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province