Streptococcus pneumoniae serotype 33H: a novel serotype with frameshift mutations in the acetyltransferase gene wciG
Here, we have provided serological, genetic and biochemical evidence that the 33G-like capsule differs to 33G and all other pneumococcal serotypes, meeting the requirements to be designated as a new serotype, which we have named 33H.
Authors
- Jason Hinds (ORCID: https://orcid.org/0000-0002-2739-1908)
- Kim Mulholland (ORCID: https://orcid.org/0000-0001-7947-680X)
- Stephanie W. Lo (ORCID: https://orcid.org/0000-0002-2182-0222)
- Markus Hilty (ORCID: https://orcid.org/0000-0002-2418-6474)
- Neil Ravenscroft (ORCID: https://orcid.org/0000-0001-8476-5630)
- Belinda D. Ortika (ORCID: https://orcid.org/0000-0001-7710-5124)
- Fiona M. Russell (ORCID: https://orcid.org/0000-0002-3077-9639)
- Joel P. Werren (ORCID: https://orcid.org/0000-0002-4822-130X)
- Odgerel Tundev
- Claire von Mollendorf (ORCID: https://orcid.org/0000-0003-0927-1731)
- Tuya Mungun
- Bradford D. Gessner (ORCID: https://orcid.org/0000-0002-6216-7194)
- Ilche Gjuroski (ORCID: https://orcid.org/0000-0002-7508-9789)
- Stephen D. Bentley (ORCID: https://orcid.org/0000-0001-8094-3751)
- Catherine Satzke (ORCID: https://orcid.org/0000-0003-3164-8849)
- Casey L. Pell (ORCID: https://orcid.org/0000-0003-3883-2163)
- Sam Manna (ORCID: https://orcid.org/0000-0002-7694-9605)
- Eileen Margaret Dunne (ORCID: https://orcid.org/0000-0001-5542-0780)
Institutions
- University of Bern (CH)
- University of Cape Town (ZA)
- The University of Melbourne (AU)
- St George's, University of London (GB)
- Pfizer (United States) (US)
- Wellcome Sanger Institute (GB)
- National Center for Communicable Diseases (MN)
- London School of Hygiene & Tropical Medicine (GB)
- Peter Doherty Institute (AU)
- Ministry of Health (MN)
- Murdoch Children's Research Institute (AU)
- University of Bath (GB)
Publication Details
- Journal
- Pneumonia
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1186/s41479-025-00162-2
- Citations
- 11
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 14.90
Funders
- Pfizer