A chiral HPLC and pharmacokinetic approach of 1-(4-bromophenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide

We successfully established optimized bioanalytical method for pharmacokinetic study were both the enantiomers were properly separated. In pharmacokinetic activity we found that the enantiomers are non-stereoselective having same absorption rate.

Authors

Bannimath Gurupadayya (ORCID: https://orcid.org/0000-0001-7590-5160)
Honnavalli Yogish Kumar (ORCID: https://orcid.org/0000-0002-3798-0837)
K. S. Chethan
Michael D. Shelby
Peddaguravagari Mounika

Institutions

JSS Academy of Higher Education and Research (IN)

Publication Details

Journal: Bioanalysis
Published: 2025-03-24
DOI: https://doi.org/10.1080/17576180.2025.2481023
Primary Topic: Chemical synthesis and alkaloids
Type: article
Field-Weighted Citation Impact: 0.00

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article

A chiral HPLC and pharmacokinetic approach of 1-(4-bromophenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide

Bannimath Gurupadayya, Honnavalli Yogish Kumar, K. S. Chethan, Michael D. Shelby et al.

Mar 24, 2025

Bioanalysis

Chemical synthesis and alkaloids

article

A chiral HPLC and pharmacokinetic approach of 1-(4-bromophenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide

Bannimath Gurupadayya, Honnavalli Yogish Kumar, K. S. Chethan, Michael D. Shelby, Peddaguravagari Mounika

March 24, 2025article en

Abstract

BioanalysisVol. 17(7)

JSS Academy of Higher Education and Research (IN)

Openalex Percentile: Top 96%

Chemical synthesis and alkaloids

DOI Open Access PDF OpenAlex

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A chiral HPLC and pharmacokinetic approach of 1-(4-bromophenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide — Bannimath Gurupadayya, Honnavalli Yogish Kumar, et al. · Bioanalysis (2025) | TGRS Research Map | TGRS