Duration of resuscitation, regain of consciousness and histopathological severity of hypoxic-ischemic encephalopathy after cardiac arrest
We found less SEND and RoC was more likely in patients with shorter tROSCs. A tROSC less than 1 min was mostly associated with SEND less than 30% in all brain regions. Prolonged resuscitations with tROSCs greater than 20 min did not exclude a SEND less than 30% in a relevant proportion of patients. Future histopathological studies are warranted to investigate the impact of modifiable clinical parameters on the severity of HIE.
Authors
- Jens Nee
- Christoph J. Ploner (ORCID: https://orcid.org/0000-0003-0983-4530)
- Christoph Leithner (ORCID: https://orcid.org/0000-0002-8277-846X)
- Christian Storm (ORCID: https://orcid.org/0000-0002-8286-1650)
- Werner Stenzel (ORCID: https://orcid.org/0000-0002-1143-2103)
- Sandra Preuß
- Christian Endisch
- K. N. Millard
Institutions
- Supply Chain Competence Center (Germany) (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Resuscitation Plus
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1016/j.resplu.2025.100945
- Citations
- 1
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 2.25
Funders
- ZOLL Foundation
- Laerdal Foundation for Acute Medicine
- Berlin Institute of Health