The Association Between Dysglycemia and Endotheliopathy in ICU Patients With and Without Diabetes: A Cohort Study
In acutely admitted adult ICU patients, hypoglycemia was associated with endotheliopathy regardless of preadmission diabetes status. Hyperglycemia and high glycemic variability were associated with endotheliopathy in patients without diabetes. This suggests different responses to acute dysglycemia in patients with and without diabetes and warrants further investigation in clinical trials.
Authors
- Martin Schønemann‐Lund (ORCID: https://orcid.org/0000-0001-5116-509X)
- Pär I. Johansson (ORCID: https://orcid.org/0000-0001-9778-5964)
- Ulrik Pedersen‐Bjergaard (ORCID: https://orcid.org/0000-0003-0588-4880)
- Christian Gantzel Nielsen (ORCID: https://orcid.org/0000-0002-5105-1049)
- Mikkel Thor Olsen (ORCID: https://orcid.org/0000-0003-2474-6168)
- Morten H. Bestle (ORCID: https://orcid.org/0000-0001-6585-2659)
- Peter Lommer Kristensen (ORCID: https://orcid.org/0000-0001-5431-824X)
Institutions
- University of Copenhagen (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Zealand University Hospital (DK)
Publication Details
- Journal
- Critical Care Explorations
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1097/cce.0000000000001229
- Primary Topic
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sanofi
- Novo Nordisk
- Nordsjællands Hospital