Microbiota-derived resveratrol metabolites: New biomarkers of red wine consumption are inversely associated with inflammation in a longitudinal study of a Mediterranean population
Light to moderate red wine consumption (10 to 20 grams of alcohol per day), which can be monitored by microbiota-derived resveratrol metabolites excreted in urine, is associated with lower plasma concentrations of sVCAM-1, an inflammatory biomarker related to atherosclerosis. Biomarkers of consumption offer advantages compared to FFQ data, since they provide objective and more accurate information about nutrient intake and metabolism. Without specific biomarkers of red wine consumption, no significant associations would have been found in the present study.
Authors
- Montserrat Fitó (ORCID: https://orcid.org/0000-0002-1817-483X)
- Rosa Casas (ORCID: https://orcid.org/0000-0002-0211-9166)
- Maria Pérez (ORCID: https://orcid.org/0000-0001-5775-6472)
- Rosa Maria Lamuela-Raventós (ORCID: https://orcid.org/0000-0002-1287-4560)
- Polina А. Galkina (ORCID: https://orcid.org/0000-0003-3499-4069)
- Inés Domínguez‐López (ORCID: https://orcid.org/0000-0001-9682-743X)
- Emilio Ros (ORCID: https://orcid.org/0000-0002-2573-1294)
- Miguel Ángel González Martínez (ORCID: https://orcid.org/0000-0002-5104-1262)
- Francesc M. Campins-Machado (ORCID: https://orcid.org/0009-0006-2162-1756)
- Ramón Estruch (ORCID: https://orcid.org/0000-0003-1260-4445)
Institutions
- Instituto de Salud Carlos III (ES)
Publication Details
- Journal
- The journal of nutrition health & aging
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1016/j.jnha.2025.100542
- Citations
- 3
- Primary Topic
- Tea Polyphenols and Effects
- Type
- article
- Field-Weighted Citation Impact
- 4.41