Mediastinal staging lymph node probability map in non-small cell lung cancer
A total of 116 patients with a mean age of 66, 93% of whom were men, were included. 358 lymph nodes were evaluated, 51% of which exhibited adenocarcinoma and 35% were squamous, while 14% were classified as non-small-cell lung carcinoma. The model estimated the probability of malignancy for each lymph node using age, DSA, SUVmax, and AR. The Area Under the ROC curve, was 0.89. A user-friendly application was also developed ( https://ubidi.shinyapps.io/lymma/ .) CONCLUSIONS: The integration of patient clinical characteristics, EBUS features, and PET/CT findings may generate a pre-sampling malignancy probability map for each lymph node. The model requires prospective and external validation.
Authors
- J.L. Vercher-Conejero (ORCID: https://orcid.org/0000-0002-5091-4973)
- P.C. Notta
- Guillermo Rodriguez-González
- Rosa López‐Lisbona
- C. Cabeza
- Jaume Bordas-Martínez (ORCID: https://orcid.org/0000-0003-4027-8907)
- Cristian Tebé (ORCID: https://orcid.org/0000-0003-2320-1385)
- Noelia Cubero
- Salud Santos (ORCID: https://orcid.org/0000-0002-5835-1028)
- Marta Díez-Ferrer (ORCID: https://orcid.org/0000-0002-0207-8157)
- Antoni Rosell (ORCID: https://orcid.org/0000-0003-0877-7191)
- Montserrat Cortés‐Romera
Institutions
- Bellvitge University Hospital (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Hospital General de Granollers (ES)
- Hospital Clínico Universitario de Valladolid (ES)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1186/s12931-025-03121-z
- Citations
- 1
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52