A Cu/Cd-cocatalysed cascade reaction for constructing nitrogen-tethered 1,6-enynes enabled by 1,5-hydride transfer
A versatile multi-component protocol for modular access to nitrogen-tethered 1,6-enynes via Cu/Cd-cocatalysed domino A 3 -coupling/1,5-hydride transfer/α-alkynylation using secondary amines, formaldehyde and alkynes is developed.
Authors
- Liliang Huang (ORCID: https://orcid.org/0000-0002-1412-1431)
- Junhai Huang (ORCID: https://orcid.org/0000-0002-0723-3507)
- Huangdi Feng (ORCID: https://orcid.org/0000-0002-5500-8283)
- Tiantian Zhang (ORCID: https://orcid.org/0000-0002-2283-4888)
- Hexiang Wang
Institutions
- Shanghai University of Engineering Science (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00174a
- Citations
- 2
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 1.07