One-Month Silicone Oil Tamponade Can Decrease Intraocular Complications via Reducing the Recruitment and Activation of Leukocytes in Patients with Rhegmatogenous Retinal Detachment
One-month SO tamponade significantly reduces intraocular inflammatory cytokine levels and associated complications by decreasing the recruitment and activation of leukocytes. These findings suggest that shorter SO placement durations can effectively minimize inflammation-related complications while maintaining therapeutic efficacy. Future research should focus on optimizing SO tamponade protocols and exploring the underlying mechanisms of inflammation and emulsification to enhance the safety and efficacy of vitreoretinal surgeries.
Authors
- Ziye Chen (ORCID: https://orcid.org/0000-0002-1866-0803)
- Yuqing Wu (ORCID: https://orcid.org/0000-0002-5568-2390)
- Zhuangling Lin (ORCID: https://orcid.org/0000-0002-9235-9349)
- Baoyi Liu (ORCID: https://orcid.org/0000-0001-5764-4817)
- Zijian Qin (ORCID: https://orcid.org/0000-0002-5458-7906)
- Kunbei Lai (ORCID: https://orcid.org/0009-0002-9116-3368)
- Lan Jiang (ORCID: https://orcid.org/0000-0001-5947-5922)
- Zhuojun Xu
- Tao Li (ORCID: https://orcid.org/0000-0001-8064-871X)
- Zitong Chen (ORCID: https://orcid.org/0000-0003-3467-7311)
- Chin-Ling Tsai
- Yuan Ma (ORCID: https://orcid.org/0000-0002-8050-5257)
Institutions
- Sun Yat-sen University (CN)
- Chinese University of Hong Kong (HK)
- Shantou University (CN)
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Ophthalmic Research
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1159/000545211
- Citations
- 2
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 2.72