Clinical characteristics of pregnancy after IVF in patients with infertility of various etiologies

Objective. To study and emphasize the most significant anamnestic factors and aspects of pregnancy course after IVF with autologous oocytes that require a change in the follow-up plan and a reasonable approach to the hospitalization of pregnant women in the maternity hospital. Patients and methods. The study included 181 women who had a successful childbirth. They were divided into three groups depending on the leading cause of infertility: group 1 – 64 patients with chronic endometritis and “thin endometrium”; group 2 – 55 pregnant women with tubal-peritoneal infertility; group 3 – 62 women with male factor infertility. Results. Pregnant women with different leading causes of infertility differ in the probability of exacerbation of chronic inflammation in the kidneys and urinary tract. In women with thin endometrium as a cause of infertility, the duration of progestogen administration and the total mean duration of hospitalization until 22 weeks’ gestation were statistically significantly longer compared to other groups, and the duration of hospitalization after 22 weeks was longer compared to the group with male infertility factor. They were also found to have more cases of threatened preterm labor, intrauterine growth restriction and preeclampsia. Conclusion. After IVF, women with thin endometrium as a cause of infertility require longer progesterone administration, which does not reduce the duration of hospitalization and indications for prenatal hospitalization. Key words: female infertility, thin endometrium, in vitro fertilization, pregnancy, progesterone medications, duration of hospitalization