Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye

Our results corroborate that unilateral optic nerve injury elicits a microglial response in the uninjured contralateral eye but without RGC loss. Therefore, the contralateral eye should be treated separately and not as an ONC control.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-03-24
DOI
https://doi.org/10.1167/iovs.66.3.49
Citations
3
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
5.12

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article

Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye

Sandra Siegert, Gloria Colombo, Margaret E. Maes, Florianne E. Schoot Uiterkamp et al.
3 citations
Investigative Ophthalmology & Visual Science
Glaucoma and retinal disorders
5.12
article

Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye

Sandra Siegert, Gloria Colombo, Margaret E. Maes, Florianne E. Schoot Uiterkamp, Arsalan Firoozi, Mohammad Amin Alamalhoda
article en
3 citations

Abstract

Our results corroborate that unilateral optic nerve injury elicits a microglial response in the uninjured contralateral eye but without RGC loss. Therefore, the contralateral eye should be treated separately and not as an ONC control.

Investigative Ophthalmology & Visual ScienceVol. 66(3)
Institute of Science and Technology Austria (AT)
Institute of Science and Technology Austria, Austrian Science Fund
Openalex Percentile: Top 5%
Glaucoma and retinal disorders
5.12
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