Memory B cell proliferation drives differences in neutralising responses between ChAdOx1 and BNT162b2 SARS-CoV-2 vaccines
Reconstructing in-host kinetics in response to vaccination could help optimise vaccine dosing regimens, improve vaccine efficacy in different population groups, and inform the design of future vaccines for enhanced protection against emerging pathogens.
Authors
- David Hodgson (ORCID: https://orcid.org/0000-0002-5585-8974)
- Annette Fox (ORCID: https://orcid.org/0000-0002-0565-7146)
- Siddhartha Mahanty (ORCID: https://orcid.org/0000-0003-1068-0524)
- Sheena G. Sullivan (ORCID: https://orcid.org/0000-0002-0856-0294)
- Louise Carolan
- Kanta Subbarao (ORCID: https://orcid.org/0000-0003-1713-3056)
- Yi Liu (ORCID: https://orcid.org/0000-0002-2051-440X)
- Adam Kucharski
Institutions
- The Royal Melbourne Hospital (AU)
- The University of Melbourne (AU)
- London School of Hygiene & Tropical Medicine (GB)
- Peter Doherty Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-24
- DOI
- https://doi.org/10.3389/fimmu.2025.1487066
- Citations
- 5
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 6.98
Funders
- U.S. Department of Health and Human Services
- University of Rochester
- Australian Government
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases