Association between monocyte-to-lymphocyte ratio and cardiovascular diseases: insights from NHANES data
Compared with other inflammatory indicators (SIRI, AISI, and CAR), MLR appears to be a better inflammatory index for predicting CVD, CHF, CHD, angina pectoris, heart attack, and stroke. American adults with elevated MLR and SIRI should be aware of the possible harm caused by CVD. Causal inference is, however, limited by the cross-sectional design and dependence on self-reported data. Further longitudinal studies are needed to validate these findings.
Authors
- X.B. Li (ORCID: https://orcid.org/0000-0002-6071-0392)
- Yiru Shen (ORCID: https://orcid.org/0000-0002-7263-1632)
- Juan Zhou (ORCID: https://orcid.org/0000-0002-1066-1262)
- Yantian Gong (ORCID: https://orcid.org/0009-0000-3063-9946)
- Junjie Wang (ORCID: https://orcid.org/0000-0002-1388-076X)
- Sheng Wang (ORCID: https://orcid.org/0000-0003-3439-4696)
- Yingying Du (ORCID: https://orcid.org/0000-0002-1205-5012)
- Liyan Zhang (ORCID: https://orcid.org/0000-0001-6549-664X)
Institutions
- Tongji University (CN)
- Shanghai Tenth People's Hospital (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1186/s13098-025-01640-9
- Citations
- 11
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 11.50
Funders
- National Natural Science Foundation of China