Lipoplastic Lymphadenopathy: A Rare Cause for Generalized Lymphadenopathy

Lipoplastic lymphadenopathy (also called lipolymph) is a histopathological benign condition in which there is excess ectopic adipose tissue in the lymph node causing its enlargement. We present a 30-year-old man with no past medical history of note, admitted with pallor, easy bruises, and fatigue. He has iron deficiency anemia. He has also generalized lymphadenopathy. Computed Tomography (CT) of the chest, abdomen, and pelvis with IV contrast showed generalized low attenuation lymph nodes. Excisional biopsy was done to exclude hematological malignancy which was diagnosed as lipoplastic lymphadenopathy. He was managed with intravenous iron and packed red blood cell (PRBCs) transfusion and discharged in a stable condition.