Electrochemical α-hydroxylation of aryl ketones with methanol as the oxygen source
We developed an electrochemical method for direct α-C(sp 3 )–H hydroxylation of aryl ketones using methanol as an oxygen donor and Br − as redox mediators. Notably, the use of CD 3 OD enables direct synthesis of α-deuterated hydroxyketones.
Authors
- Yuan Zhou (ORCID: https://orcid.org/0000-0003-1962-2574)
- Jianhang Huang (ORCID: https://orcid.org/0000-0002-1471-0770)
- Haishun Du (ORCID: https://orcid.org/0000-0002-8046-0319)
- Yaqin Wang (ORCID: https://orcid.org/0000-0003-3397-3071)
- Zhishan Yang (ORCID: https://orcid.org/0000-0003-0122-3399)
- Mingming Yu
Institutions
- Zhejiang Sci-Tech University (CN)
- Jiangxi Normal University (CN)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5gc00758e
- Citations
- 5
- Primary Topic
- Catalysis and Oxidation Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.94