Old Age, B Cell Function and Count Are the Critical Factors for Predicting Infection Risk in Patients With Autoimmune Rheumatic Diseases Undergoing Immunosuppression: A Cohort Study

Older age, low IgG, low B cell count (CD19) predict susceptibility to infections; high neutrophil counts, low platelets, and elevated NLR are key predictors of developing infection in ARDs patients. Careful monitoring and tailored treatment strategies are essential to reduce infection risks. Further research is needed in this direction to develop predictive algorithms.

Authors

Publication Details

Journal
International Journal of Rheumatic Diseases
Published
2025-03-01
DOI
https://doi.org/10.1111/1756-185x.70187
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
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article

Old Age, B Cell Function and Count Are the Critical Factors for Predicting Infection Risk in Patients With Autoimmune Rheumatic Diseases Undergoing Immunosuppression: A Cohort Study

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International Journal of Rheumatic Diseases
Systemic Lupus Erythematosus Research
article

Old Age, B Cell Function and Count Are the Critical Factors for Predicting Infection Risk in Patients With Autoimmune Rheumatic Diseases Undergoing Immunosuppression: A Cohort Study

Renuka Panchagnula, J Prakruthi, Shruti Paramshetti, Srikantiah Chandrashekara, Devaraj Kori, S Ahamed
article en

Abstract

Older age, low IgG, low B cell count (CD19) predict susceptibility to infections; high neutrophil counts, low platelets, and elevated NLR are key predictors of developing infection in ARDs patients. Careful monitoring and tailored treatment strategies are essential to reduce infection risks. Further research is needed in this direction to develop predictive algorithms.

International Journal of Rheumatic DiseasesVol. 28(3)
Good health and well-being
Openalex Percentile: Top 92%
Systemic Lupus Erythematosus Research
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