Advances in the Preparation, Structure-Activity Relationship, and Biological Mechanisms of <em>Agaricus</em> Polysaccharides
Polysaccharides derived from the <em>Agaricus</em> genus have garnered considerable attention due to their diverse biological activities and potential applications in functional foods and pharmaceuticals. This review focuses on the preparation methods, structure-activity relationships, and underlying biological mechanisms of <em>Agaricus</em> polysaccharides. Key advances in their extraction and purification techniques, structural characterization using modern analytical tools, and their association with biological activities are discussed. The role of polysaccharide structure, including glycosidic linkages, branching degrees, and molecular weight, in determining their physicochemical properties and biofunctions is highlighted. Moreover, the biological mechanisms underpinning their antitumor, immunomodulatory, antioxidant effects are elaborated. Finally, future perspectives on the challenges and opportunities for developing <em>Agaricus</em> polysaccharides as functional biomaterials are provided.
Authors
- Jianzhao Qi (ORCID: https://orcid.org/0000-0003-1418-873X)
- Ming Zhang (ORCID: https://orcid.org/0000-0001-7245-7366)
- Yuying Liu (ORCID: https://orcid.org/0000-0003-3848-9254)
- Minglei Li (ORCID: https://orcid.org/0000-0001-5432-2855)
- Zhixuan Li (ORCID: https://orcid.org/0000-0003-0482-4413)
Publication Details
- Journal
- Food Science and Human Wellness
- Published
- 2025-03-01
- DOI
- https://doi.org/10.26599/fshw.2025.9250590
- Citations
- 2
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Yakult Bio-Science Foundation
- National Key Research and Development Program of China