Mollaret's Meningitis: A Case Report of Recurrent Aseptic Meningitis

Benign recurrent meningitis, also known as Mollaret's meningitis, a rare form of recurrent aseptic meningitis, is often associated with herpes simplex virus type 2 (HSV-2) infection, which is characterized by fever, headache, meningeal irritation, and sterility of the cerebrospinal fluid (CSF) on examination. Although with clear diagnostic criteria, there are still many equivocal aspects of its pathogenesis and treatment. This paper presents a case report of a 40-year-old woman who experienced multiple episodes of this syndromic condition, highlighting its diagnostic challenges, clinical features, and treatment outcomes. The case reflects the importance of timely diagnosis and intervention in managing Mollaret's meningitis effectively. Furthermore, it sheds light on the complexities of its etiology and potential predisposing factors and the need for further research to better understand this condition.

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Publication Details

Journal
Cureus
Published
2025-03-24
DOI
https://doi.org/10.7759/cureus.81065
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Mollaret's Meningitis: A Case Report of Recurrent Aseptic Meningitis

Justin Nolte, Jason W. Adams, Jean‐Pierre J. Issa, Danial Bajwa et al.
Cureus
Herpesvirus Infections and Treatments
article

Mollaret's Meningitis: A Case Report of Recurrent Aseptic Meningitis

Justin Nolte, Jason W. Adams, Jean‐Pierre J. Issa, Danial Bajwa, Syed Hashim Ali Inam, Paul Ferguson, Fahim Barmak
article en

Abstract

Benign recurrent meningitis, also known as Mollaret's meningitis, a rare form of recurrent aseptic meningitis, is often associated with herpes simplex virus type 2 (HSV-2) infection, which is characterized by fever, headache, meningeal irritation, and sterility of the cerebrospinal fluid (CSF) on examination. Although with clear diagnostic criteria, there are still many equivocal aspects of its pathogenesis and treatment. This paper presents a case report of a 40-year-old woman who experienced multiple episodes of this syndromic condition, highlighting its diagnostic challenges, clinical features, and treatment outcomes. The case reflects the importance of timely diagnosis and intervention in managing Mollaret's meningitis effectively. Furthermore, it sheds light on the complexities of its etiology and potential predisposing factors and the need for further research to better understand this condition.

CureusVol. 17(3)
Army Medical College (PK), Marshall University (US)
Good health and well-being
Openalex Percentile: Top 92%
Herpesvirus Infections and Treatments
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