Massive Osteolysis of the Mandible in Gorham’s Disease: Our Case Experience

Vanishing bone disease is an exceptionally rare condition marked by the progressive loss of bone, ultimately leading to its complete disappearance. The cause of this disease remains unknown, and it primarily affects the axial skeleton, pelvis, and humerus. Due to its atypical presentation and rarity, it is often mistaken for other disorders, making an accurate diagnosis challenging and typically a process of elimination. Gorham's disease has been documented in the maxillofacial region, with most involving the mandible. We present a case involving a 14-year-old male patient who exhibited Gorham's disease in the right mandible, characterized by the loosening of teeth.

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Publication Details

Journal
Cureus
Published
2025-03-24
DOI
https://doi.org/10.7759/cureus.81063
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
Field-Weighted Citation Impact
0.00
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article

Massive Osteolysis of the Mandible in Gorham’s Disease: Our Case Experience

Arunkumar Kamalakaran, Balaji Jayaraman, Dakshayani Balaji, Kamalakannan Padmanaban et al.
Cureus
Vascular Malformations and Hemangiomas
article

Massive Osteolysis of the Mandible in Gorham’s Disease: Our Case Experience

Arunkumar Kamalakaran, Balaji Jayaraman, Dakshayani Balaji, Kamalakannan Padmanaban, Nazmul Ahamed
article en

Abstract

Vanishing bone disease is an exceptionally rare condition marked by the progressive loss of bone, ultimately leading to its complete disappearance. The cause of this disease remains unknown, and it primarily affects the axial skeleton, pelvis, and humerus. Due to its atypical presentation and rarity, it is often mistaken for other disorders, making an accurate diagnosis challenging and typically a process of elimination. Gorham's disease has been documented in the maxillofacial region, with most involving the mandible. We present a case involving a 14-year-old male patient who exhibited Gorham's disease in the right mandible, characterized by the loosening of teeth.

CureusVol. 17(3)
Tamil Nadu Government Dental College and Hospital (IN)
Openalex Percentile: Top 91%
Vascular Malformations and Hemangiomas
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Massive Osteolysis of the Mandible in Gorham’s Disease: Our Case Experience — Arunkumar Kamalakaran, Balaji Jayaraman, et al. · Cureus (2025) | TGRS Research Map | TGRS