Effect of phytocomposition on dyslipidemia in patients with SARS-CoV-2 infection at the health resort stage of treatment

Background . Cardiovascular events are the main threat in the post-COVID period, and their risk is increased in patients who have had a new coronavirus infection (SARS-CoV-2). In this regard, the direction of studying the correction of already well-studied modifiable risk factors is of particular relevance. One of such factors is certainly dyslipidemia. The aim . To study the level of blood lipids in patients after new coronavirus infection and the possibility of its correction during rehabilitation in sanatorium conditions with the additional use of the phytotherapy. Materials and methods. The study included 50 people who, according to their medical history, had suffered from SARS-CoV-2 infection and were admitted to sanatorium treatment. All patients underwent a course of rehabilitation measures lasting 20 days. Before and after the course of rehabilitation, patients underwent laboratory analysis, which included the main biochemical parameters, including total cholesterol, lowdensity lipoproteins, high-density lipoproteins and triglycerides. The respondents were divided into two groups – experimental (group 1; n = 21) and control (group 2; n = 29). Patients from group 1 received tea from a phytocomposition in addition to standard measures. Results . In the group receiving tea based on herbal phytocomposition, there was a statistically significant decrease in total cholesterol from 6.91 ± 1.75 to 5.9 ± 1.64 mmol/l (p = 0.04) and low-density lipoproteins from 4.68 ± 1.65 to 3.78 ± 1.28 mmol/l (p = 0.038). No changes were detected in these indicators, as well as in the level of triglycerides in group 2. Conclusion . The use of the phytocomposition presented in the study during the course allowed a statistically significant reduction in low-density lipoproteins levels in the blood of post-Covid patients by more than 0.9 ± 1.85 mmol/l. The use of phytopreparations in order to reduce the risk of cardiovascular events in patients who have undergone new coronavirus infection is a promising area that requires more detailed in-depth studies.

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Publication Details

Journal
Acta Biomedica Scientifica (East Siberian Biomedical Journal)
Published
2025-03-21
DOI
https://doi.org/10.29413/abs.2025-10.1.23
Primary Topic
Medicinal Plants and Bioactive Compounds
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article
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article

Effect of phytocomposition on dyslipidemia in patients with SARS-CoV-2 infection at the health resort stage of treatment

F. M. Melikov, В. А. Белоглазов, I. A. Yatskov, L. Sh. Dudchenko et al.
Acta Biomedica Scientifica (East Siberian Biomedical Journal)
Medicinal Plants and Bioactive Compounds
article

Effect of phytocomposition on dyslipidemia in patients with SARS-CoV-2 infection at the health resort stage of treatment

F. M. Melikov, В. А. Белоглазов, I. A. Yatskov, L. Sh. Dudchenko, G. N. Andreeva, E. A. Solovyova
article en

Abstract

Background . Cardiovascular events are the main threat in the post-COVID period, and their risk is increased in patients who have had a new coronavirus infection (SARS-CoV-2). In this regard, the direction of studying the correction of already well-studied modifiable risk factors is of particular relevance. One of such factors is certainly dyslipidemia. The aim . To study the level of blood lipids in patients after new coronavirus infection and the possibility of its correction during rehabilitation in sanatorium conditions with the additional use of the phytotherapy. Materials and methods. The study included 50 people who, according to their medical history, had suffered from SARS-CoV-2 infection and were admitted to sanatorium treatment. All patients underwent a course of rehabilitation measures lasting 20 days. Before and after the course of rehabilitation, patients underwent laboratory analysis, which included the main biochemical parameters, including total cholesterol, lowdensity lipoproteins, high-density lipoproteins and triglycerides. The respondents were divided into two groups – experimental (group 1; n = 21) and control (group 2; n = 29). Patients from group 1 received tea from a phytocomposition in addition to standard measures. Results . In the group receiving tea based on herbal phytocomposition, there was a statistically significant decrease in total cholesterol from 6.91 ± 1.75 to 5.9 ± 1.64 mmol/l (p = 0.04) and low-density lipoproteins from 4.68 ± 1.65 to 3.78 ± 1.28 mmol/l (p = 0.038). No changes were detected in these indicators, as well as in the level of triglycerides in group 2. Conclusion . The use of the phytocomposition presented in the study during the course allowed a statistically significant reduction in low-density lipoproteins levels in the blood of post-Covid patients by more than 0.9 ± 1.85 mmol/l. The use of phytopreparations in order to reduce the risk of cardiovascular events in patients who have undergone new coronavirus infection is a promising area that requires more detailed in-depth studies.

Acta Biomedica Scientifica (East Siberian Biomedical Journal)Vol. 10(1)
Russian Academy of Sciences (RU), Nikita Botanical Gardens (RU), Research Institute of Medical Climatology and Rehabilitation (RU), V.I. Vernadsky Crimean Federal University (UA)
Openalex Percentile: Top 95%
Medicinal Plants and Bioactive Compounds
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