Optimizing early detection of uterine cancer in women with risk factors

The article describes the stages of early detection of uterine body cancer in patients with morbid obesity. It has been proven that genetic testing for oncogenic mutations of endocervical canal scrapings with a negative cytological conclusion regarding cervical cancer is effective for subsequent screening of uterine body cancer. In morbid obesity, the diagnostic sensitivity of mutation screening for uterine body cancer increases when examining endocervical canal scrapings. When oncogenic mutations are detected in samples from the endocervical canal, the next step is recommended to conduct a cytological examination of endometrial biopsies with sampling using brush technology.

Authors

Publication Details

Journal
Yakut Medical Journal
Published
2025-03-17
DOI
https://doi.org/10.25789/ymj.2025.89.03
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Optimizing early detection of uterine cancer in women with risk factors

A. Yu. Maksimov, Ekaterina V. Verenikina, N. V. Karasenko, А. А. Демидова et al.
Yakut Medical Journal
Endometrial and Cervical Cancer Treatments
article

Optimizing early detection of uterine cancer in women with risk factors

A. Yu. Maksimov, Ekaterina V. Verenikina, N. V. Karasenko, А. А. Демидова, M. Yu. Grafskaya, Mariya V. Ermilova
article en

Abstract

The article describes the stages of early detection of uterine body cancer in patients with morbid obesity. It has been proven that genetic testing for oncogenic mutations of endocervical canal scrapings with a negative cytological conclusion regarding cervical cancer is effective for subsequent screening of uterine body cancer. In morbid obesity, the diagnostic sensitivity of mutation screening for uterine body cancer increases when examining endocervical canal scrapings. When oncogenic mutations are detected in samples from the endocervical canal, the next step is recommended to conduct a cytological examination of endometrial biopsies with sampling using brush technology.

Yakut Medical Journal(1)
Openalex Percentile: Top 92%
Endometrial and Cervical Cancer Treatments
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