Radial scar of the breast as a mask of malignant neoplasms

In order to study the radial scar as a mask of malignancy, a literature review was conducted. It was found that the difficulty in diagnosing the radial scar is due to its morphological similarity to a malignancy and associated intraductal epithelial proliferations. To exclude a malignancy and intraductal proliferations, immunohistochemical visualization of the intact myoepithelial cell layer is used, as well as cellular heterogeneity of intraductal proliferations using markers such as p63, basal cytokeratins, smooth muscle actin, basal cytokeratins, and estrogen receptor. It was found that in the case of a combination of a radial scar with atypia or other high-risk lesions of the mammary gland, the likelihood of its transformation into malignant lesions of the mammary gland increases.