Evaluation of the Diagnostic Accuracy of the T2Resistance Panel (Research Use Only) in Patients With Possible Bacterial Bloodstream Infections
T2R testing is highly specific (100%) for the 13 antibiotic resistance genes on the panel. Sensitivity was 100% for the genes detected but was low (17%) for coagulase-negative staphylococci. T2R testing has the potential to diagnose certain antibiotic resistance genes from bacterial bloodstream infections in hours vs the days required for a positive blood culture with AST. Additional studies that include larger numbers of samples with antimicrobial resistance genes are needed.
Authors
- J Pierre (ORCID: https://orcid.org/0000-0001-5525-6896)
- George A. Pankey (ORCID: https://orcid.org/0000-0002-9130-4418)
- Royanne H Vortisch
- Heather Davis (ORCID: https://orcid.org/0000-0001-9522-8080)
- Deborah Ashcraft
- Samantha Smith (ORCID: https://orcid.org/0000-0002-4108-8497)
- Susan Scariano
- Maria Latsis
Institutions
- Ochsner Medical Center (US)
Publication Details
- Journal
- Ochsner Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.31486/toj.24.0101
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 0.00