Evaluation of the Diagnostic Accuracy of the T2Resistance Panel (Research Use Only) in Patients With Possible Bacterial Bloodstream Infections

T2R testing is highly specific (100%) for the 13 antibiotic resistance genes on the panel. Sensitivity was 100% for the genes detected but was low (17%) for coagulase-negative staphylococci. T2R testing has the potential to diagnose certain antibiotic resistance genes from bacterial bloodstream infections in hours vs the days required for a positive blood culture with AST. Additional studies that include larger numbers of samples with antimicrobial resistance genes are needed.

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Publication Details

Journal
Ochsner Journal
Published
2025-01-01
DOI
https://doi.org/10.31486/toj.24.0101
Primary Topic
Bacterial Identification and Susceptibility Testing
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of the Diagnostic Accuracy of the T2Resistance Panel (Research Use Only) in Patients With Possible Bacterial Bloodstream Infections

J Pierre, George A. Pankey, Royanne H Vortisch, Heather Davis et al.
Ochsner Journal
Bacterial Identification and Susceptibility Testing
article

Evaluation of the Diagnostic Accuracy of the T2Resistance Panel (Research Use Only) in Patients With Possible Bacterial Bloodstream Infections

J Pierre, George A. Pankey, Royanne H Vortisch, Heather Davis, Deborah Ashcraft, Samantha Smith, Susan Scariano, Maria Latsis
article en

Abstract

T2R testing is highly specific (100%) for the 13 antibiotic resistance genes on the panel. Sensitivity was 100% for the genes detected but was low (17%) for coagulase-negative staphylococci. T2R testing has the potential to diagnose certain antibiotic resistance genes from bacterial bloodstream infections in hours vs the days required for a positive blood culture with AST. Additional studies that include larger numbers of samples with antimicrobial resistance genes are needed.

Ochsner JournalVol. 25(1)
Ochsner Medical Center (US)
Zero hunger
Openalex Percentile: Top 93%
Bacterial Identification and Susceptibility Testing
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Evaluation of the Diagnostic Accuracy of the T2Resistance Panel (Research Use Only) in Patients With Possible Bacterial Bloodstream Infections — J Pierre, George A. Pankey, et al. · Ochsner Journal (2025) | TGRS Research Map | TGRS