Comparison of SYSMEX CN-6000 and STAGO STA-R: Effects of hemolysis and lipemia

Both analysers demonstrated strong analytical performance, though methodological differences influenced APTT measurements. Hemolysis had a minor impact within Fraser's acceptable bias limits, whereas CN-6000 exhibited performance limitations in severely lipemic samples, necessitating preanalytical lipid-reducing strategies. These findings underscore the need for expanded reference range studies and optimised laboratory workflows to enhance coagulation testing reliability.

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Publication Details

Journal
Journal of Medical Biochemistry
Published
2025-01-01
DOI
https://doi.org/10.5937/jomb0-56377
Primary Topic
Clinical Laboratory Practices and Quality Control
Type
article
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article

Comparison of SYSMEX CN-6000 and STAGO STA-R: Effects of hemolysis and lipemia

Elif İşbilen, Seren Orhan
Journal of Medical Biochemistry
Clinical Laboratory Practices and Quality Control
article

Comparison of SYSMEX CN-6000 and STAGO STA-R: Effects of hemolysis and lipemia

Elif İşbilen, Seren Orhan
article en

Abstract

Both analysers demonstrated strong analytical performance, though methodological differences influenced APTT measurements. Hemolysis had a minor impact within Fraser's acceptable bias limits, whereas CN-6000 exhibited performance limitations in severely lipemic samples, necessitating preanalytical lipid-reducing strategies. These findings underscore the need for expanded reference range studies and optimised laboratory workflows to enhance coagulation testing reliability.

Journal of Medical BiochemistryVol. 44(5)
Medical Park Gaziantep Hospital (TR), Gaziantep University (TR)
Openalex Percentile: Top 93%
Clinical Laboratory Practices and Quality Control
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