Effect of chronic alcohol feeding using the Lieber-DeCarli diet on Alzheimer’s disease pathology in Tg2576 mice
Chronic alcohol intake, resulting in mild liver injury, caused modest but significant AD-relevant changes in aged Tg2576 mice, which correlated with liver injury; the latter suggests significant liver-brain crosstalk in an AD model of moderate alcohol intake.
Authors
- F. Guerrero Sánchez (ORCID: https://orcid.org/0000-0003-1762-6184)
- David H. Cribbs (ORCID: https://orcid.org/0000-0002-6870-4480)
- Devaraj V. Chandrashekar
- Tamara Abdullah (ORCID: https://orcid.org/0000-0002-0132-5291)
- Ross A. Steinberg (ORCID: https://orcid.org/0000-0002-3530-2557)
- Nataraj Jagadeesan (ORCID: https://orcid.org/0000-0002-2804-6145)
- Joshua Yang (ORCID: https://orcid.org/0000-0003-2410-7817)
- Rachita K. Sumbria (ORCID: https://orcid.org/0000-0002-7459-0723)
- Rudy Chang
- Derick Han (ORCID: https://orcid.org/0000-0001-7550-0438)
- Elias Khal
Institutions
- Chapman University (US)
- University of California, Irvine (US)
- Keck Graduate Institute (US)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-03-24
- DOI
- https://doi.org/10.3389/fnagi.2025.1526571
- Citations
- 1
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 1.47