Methimazole associated DRESS syndrome: a rare case

DRESS (Drug rush with Eosinophilia and Systemic Symptoms) syndrome is a rare, life-threatening idiosyncratic drug reaction characterized by acute onset of fever, skin rash, lymphhadenopathy and multisystemic organ involvement. Rapid diagnosis and treatment of patients with DRESS syndrome is crucial because of high mortality risk. Supportive therapy includes antipyretics, H1 antihistamines, humidifiers and the use of topical steroids to heal symptoms. Systemic corticosteroids can minimize symptoms of delayed hypersensitivity reactions. In this article, a case with DRESS syndrome due to use of methimazole is showed and it has been requested to take attention to DRESS syndrome.

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Publication Details

Journal
Intercontinental Journal of Emergency Medicine
Published
2025-03-17
DOI
https://doi.org/10.51271/icjem-0051
Primary Topic
Mast cells and histamine
Type
article
Field-Weighted Citation Impact
0.00
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article

Methimazole associated DRESS syndrome: a rare case

Gülhan Kurtoğlu Çelik, Nazlı Görmeli Kurt, Hakan Oğuztürk, Mehmet Güllüoğlu et al.
Intercontinental Journal of Emergency Medicine
Mast cells and histamine
article

Methimazole associated DRESS syndrome: a rare case

Gülhan Kurtoğlu Çelik, Nazlı Görmeli Kurt, Hakan Oğuztürk, Mehmet Güllüoğlu, Furkan Altaş
article en

Abstract

DRESS (Drug rush with Eosinophilia and Systemic Symptoms) syndrome is a rare, life-threatening idiosyncratic drug reaction characterized by acute onset of fever, skin rash, lymphhadenopathy and multisystemic organ involvement. Rapid diagnosis and treatment of patients with DRESS syndrome is crucial because of high mortality risk. Supportive therapy includes antipyretics, H1 antihistamines, humidifiers and the use of topical steroids to heal symptoms. Systemic corticosteroids can minimize symptoms of delayed hypersensitivity reactions. In this article, a case with DRESS syndrome due to use of methimazole is showed and it has been requested to take attention to DRESS syndrome.

Intercontinental Journal of Emergency MedicineVol. 3(1)
Openalex Percentile: Top 94%
Mast cells and histamine
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