Alterations in the renin-angiotensin system during septic shock
Septic shock was associated with increased Ang I/Ang II and Ang-(1-7)/Ang II ratios, along with reduced cACE activity, increased cACE2 activity, and elevated cDPP3 concentrations compared to healthy controls.
Authors
- Raphaël Favory (ORCID: https://orcid.org/0000-0001-7772-2608)
- Adrien Picod (ORCID: https://orcid.org/0000-0002-0639-5598)
- Jacques Créteur (ORCID: https://orcid.org/0000-0003-1405-7852)
- Matthieu Legrand (ORCID: https://orcid.org/0000-0001-9788-5316)
- Marianne Rooman (ORCID: https://orcid.org/0000-0002-3810-7802)
- Bruno Garcia (ORCID: https://orcid.org/0000-0001-6650-1594)
- Fabrizio Pucci (ORCID: https://orcid.org/0000-0003-2916-022X)
- Filippo Annoni (ORCID: https://orcid.org/0000-0002-1271-9034)
- Fabio Silvio Taccone
- Jean-Louis Vincent
- Camille Benaroua
Institutions
- Université Libre de Bruxelles (BE)
- Inserm (FR)
- University of California, San Francisco (US)
- Université Paris Cité (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Sorbonne Paris Cité (FR)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1186/s13613-025-01463-x
- Citations
- 6
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 7.77
Funders
- Fonds De La Recherche Scientifique - FNRS