Photoredox Radical Cyclization of <i>o</i>-Vinylaryl Isocyanides and Aryldiazonium Tetrafluoroborates for the Synthesis of 2,4-Disubstituted Quinolines
Quinolines, a significant part of nitrogen-containing heterocycles, are widely found in functional compounds. Herin, a photochemical radical cyclization reaction of <i>o</i>-vinylaryl isocyanides and aryldiazonium tetrafluoroborates, has been reported to build 2,4-diaryl quinolines. Readily accessible aryl diazonium salts were utilized as aryl radical precursors at room temperature. This approach allowed good functional group tolerance and substrate applicability.
Authors
- Min Gao (ORCID: https://orcid.org/0000-0003-0127-7477)
- R.-Q. Xie
- Peng‐Fei Huang (ORCID: https://orcid.org/0000-0002-1154-4180)
- Chuan Ding (ORCID: https://orcid.org/0000-0001-9560-8585)
- Yu Liu (ORCID: https://orcid.org/0000-0003-4555-8238)
Institutions
- Hunan Institute of Science and Technology (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1021/acs.joc.4c03121
- Citations
- 9
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 8.42
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province
- Scientific Research Foundation of Hunan Provincial Education Department