Pan-cancer analysis of co-inhibitory molecules revealing their potential prognostic and clinical values in immunotherapy
These co-inhibitory molecules have the potential to serve as prognostic biomarkers and therapeutic targets for a broad spectrum of cancers, given their strong associations with key clinical metrics. Furthermore, the analysis results indicate that VISTA may represent a promising target for cancer therapy.
Authors
- Lei Shi (ORCID: https://orcid.org/0000-0003-4027-2396)
- Jiahui Geng (ORCID: https://orcid.org/0000-0002-4205-8230)
- Xue Wang (ORCID: https://orcid.org/0000-0003-1149-9700)
- Yuling Chen (ORCID: https://orcid.org/0000-0003-3852-9041)
- Xiaofeng Ren (ORCID: https://orcid.org/0000-0002-2120-9239)
- Lian Zhou (ORCID: https://orcid.org/0000-0002-7705-5945)
- Anjie Guo
Institutions
- Chongqing University (CN)
- Chongqing Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-24
- DOI
- https://doi.org/10.3389/fimmu.2025.1544104
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 4.18