Emo@KP MBs Modulates the TGF-β1/Smad Signaling Pathway by in situ Micro-Nano Conversion to Reduce Renal Inflammation and Fibrosis Caused by Unilateral Ureteral Obstruction
Emo@KP MBs enhanced drug delivery efficiency and therapeutic efficacy through αKIM-1 targeting and UTMD, while providing real-time imaging capabilities, suggesting good potential as a therapeutic approach to reduce renal inflammation and fibrosis in UUO.
Authors
- Yuanjing Li (ORCID: https://orcid.org/0000-0002-1525-5538)
- Xiaolong Liang (ORCID: https://orcid.org/0000-0001-7299-3329)
- Yingdong Lu (ORCID: https://orcid.org/0000-0003-4369-4084)
- Xinxin Xie (ORCID: https://orcid.org/0000-0002-4475-6673)
- Haonan Wang (ORCID: https://orcid.org/0009-0009-9625-1042)
- Lijuan Zhang (ORCID: https://orcid.org/0000-0002-9765-1875)
- Ling Zhang (ORCID: https://orcid.org/0000-0001-5304-5569)
- Wei Jing (ORCID: https://orcid.org/0000-0003-3318-1090)
- Jinxia Zhang (ORCID: https://orcid.org/0000-0002-5232-8222)
- Pengcheng Shi (ORCID: https://orcid.org/0000-0003-2504-9890)
- Xiaoning Liu (ORCID: https://orcid.org/0000-0002-6794-8600)
- Ligang Cui (ORCID: https://orcid.org/0000-0003-2258-0053)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Peking University Third Hospital (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/ijn.s499550
- Citations
- 3
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 6.02