Single-nucleus RNA sequencing reveals dynamic changes in the microenvironment of visceral adipose tissue and metabolic characteristics after cold exposure
This research provides valuable insights into the cellular heterogeneity, adipocyte remodeling, and metabolic reprogramming in eWAT after cold exposure. It highlights the critical role of transcriptional dynamics in eWAT during cold exposure and provides new perspectives on the prevention and treatment of metabolic diseases.
Authors
- Yuyu Hu
- Ting Yi (ORCID: https://orcid.org/0000-0003-4626-5285)
- Shangpeng Yang (ORCID: https://orcid.org/0009-0002-0576-7297)
- Jun Li
- Yongqiang Zhang (ORCID: https://orcid.org/0000-0003-2214-6812)
- Xi Li (ORCID: https://orcid.org/0000-0002-5456-8668)
- Li Zhang (ORCID: https://orcid.org/0000-0003-0516-762X)
- Shuai Wu (ORCID: https://orcid.org/0000-0002-4670-8915)
- Yusha Yang
- Guanyu Zhang (ORCID: https://orcid.org/0000-0003-0965-218X)
- Danfeng Yang (ORCID: https://orcid.org/0000-0003-4422-4180)
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Guiyang Medical University (CN)
- Academy of Military Medical Sciences (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-03-24
- DOI
- https://doi.org/10.3389/fendo.2025.1562431
- Citations
- 3
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 3.49