Numerical approaches for non-local transport-dominated PDE models with applications to biology

Transport-dominated partial differential equation models have been used extensively over the past two decades to describe various collective migration phenomena in cell biology and ecology. To understand the behaviour of these models (and the biological systems they describe) different analytical and numerical approaches have been used. While the analytical approaches have been discussed by different recent review studies, the numerical approaches are still facing different open problems, and thus are being employed on a rather ad-hoc basis for each developed non-local model. The goal of this review is to summarise the basic ideas behind these transport-dominated non-local models, to discuss the current numerical approaches used to simulate these models, and finally to discuss some open problems related to the applications of these numerical methods, in particular the finite element method. This allows us to emphasize the opportunities offered by this numerical method to advance the research in this field. In addition, we present in detail some numerical schemes that we used to discretize these non-local equations; in particular a new semi-implicit scheme we introduced to stabilize the oscillations obtained with classical schemes.

Authors

Institutions

Publication Details

Journal
Computational and Applied Mathematics
Published
2025-03-22
DOI
https://doi.org/10.1007/s40314-025-03146-6
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Numerical approaches for non-local transport-dominated PDE models with applications to biology

Raluca Eftimie, Alexei Lozinski, Johan Marguet
Computational and Applied Mathematics
Mathematical Biology Tumor Growth
article

Numerical approaches for non-local transport-dominated PDE models with applications to biology

Raluca Eftimie, Alexei Lozinski, Johan Marguet
article en

Abstract

Transport-dominated partial differential equation models have been used extensively over the past two decades to describe various collective migration phenomena in cell biology and ecology. To understand the behaviour of these models (and the biological systems they describe) different analytical and numerical approaches have been used. While the analytical approaches have been discussed by different recent review studies, the numerical approaches are still facing different open problems, and thus are being employed on a rather ad-hoc basis for each developed non-local model. The goal of this review is to summarise the basic ideas behind these transport-dominated non-local models, to discuss the current numerical approaches used to simulate these models, and finally to discuss some open problems related to the applications of these numerical methods, in particular the finite element method. This allows us to emphasize the opportunities offered by this numerical method to advance the research in this field. In addition, we present in detail some numerical schemes that we used to discretize these non-local equations; in particular a new semi-implicit scheme we introduced to stabilize the oscillations obtained with classical schemes.

Computational and Applied MathematicsVol. 44(4)
Centre National de la Recherche Scientifique (FR), Université Marie et Louis Pasteur (FR), Université de Franche-Comté (FR)
Agence Nationale de la Recherche, Conseil régional de Bourgogne-Franche-Comté
Openalex Percentile: Top 93%
Mathematical Biology Tumor Growth
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Numerical approaches for non-local transport-dominated PDE models with applications to biology — Raluca Eftimie, Alexei Lozinski, et al. · Computational and Applied Mathematics (2025) | TGRS Research Map | TGRS