Case report: Persistent COVID-19 in a patient with B cell lymphoma refractory to antiviral treatment due to resistance to Remdesivir
the patient presented prolonged COVID-19 with persistence of virus detected by RT-PCR for several months. The strain sequenced presented a mutation different from all reported previously. Although it was no possible to sequence the initial strain without these mutations, our data suggests that immunocompromised patient with prolonged COVID-19 may serve as reservoir for strains of SARS-CoV-2 with resistant components in his genome.
Authors
- Andréia Medeiros Rodrigues Cardoso (ORCID: https://orcid.org/0000-0002-2682-1048)
- João Renato Rebello Pinho (ORCID: https://orcid.org/0000-0003-3999-0489)
- João Carlos de Campos Guerra (ORCID: https://orcid.org/0000-0002-4156-529X)
- Vanessa Teich (ORCID: https://orcid.org/0000-0002-8539-6037)
- Roberta Cardoso Petroni
- André Mário Doi (ORCID: https://orcid.org/0000-0002-0722-1880)
- Deyvid Amgarten (ORCID: https://orcid.org/0000-0002-2612-5990)
- Luís Fernando Aranha Camargo
- Erick Gustavo Dorlass (ORCID: https://orcid.org/0000-0001-8169-3133)
- Carolina Devite Bittante
- Bruno Graciano Ponce Romeo
- Renato de Mello Ruiz
- Luiz Eduardo Ceccon Calil de Assumpção
- Marcelo Akira Nagaoka
Institutions
- Hospital Israelita Albert Einstein (BR)
Publication Details
- Journal
- IDCases
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.idcr.2025.e02199
- Citations
- 1
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.40