Preswitch Regimens Associated With Weight Gain Among Persons With HIV who Switch to Integrase Inhibitor–Containing Regimens

Preswitch regimens containing efavirenz and TDF were associated with significant weight gain after switching to INSTI-based regimens. Our findings support the hypothesis that the weight gain observed with switching to INSTI-based regimens could be driven by stopping medications with weight-suppressing properties.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1093/ofid/ofae752
Citations
2
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
4.51

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article

Preswitch Regimens Associated With Weight Gain Among Persons With HIV who Switch to Integrase Inhibitor–Containing Regimens

Nwora Lance Okeke, Clemontina A. Davenport, Melissa K. Cutshaw, Mahmoud Harding
2 citations
Open Forum Infectious Diseases
HIV-related health complications and treatments
4.51
article

Preswitch Regimens Associated With Weight Gain Among Persons With HIV who Switch to Integrase Inhibitor–Containing Regimens

Nwora Lance Okeke, Clemontina A. Davenport, Melissa K. Cutshaw, Mahmoud Harding
article en
2 citations

Abstract

Preswitch regimens containing efavirenz and TDF were associated with significant weight gain after switching to INSTI-based regimens. Our findings support the hypothesis that the weight gain observed with switching to INSTI-based regimens could be driven by stopping medications with weight-suppressing properties.

Open Forum Infectious DiseasesVol. 12(3)
North Carolina State University (US), Duke University (US)
National Institutes of Health, Center for AIDS Research, Duke University
Good health and well-being
Openalex Percentile: Top 7%
HIV-related health complications and treatments
4.51
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