MDA5 protein mediating persistent ER stress/unfolded protein response contributes to endothelial-mesenchymal-transition of lung microvascular endothelial cell in dermatomyositis
MDA5 protein mediating persistent ER stress/UPR contributed to EndMT in vascular endothelial cells, which should be involved in MDA5 + DM related ILD.
Authors
- He-De Zhang
- Ye Hong (ORCID: https://orcid.org/0000-0001-5800-0917)
- Wanli Ma (ORCID: https://orcid.org/0000-0002-2001-3234)
- Qian Niu (ORCID: https://orcid.org/0000-0001-8685-3263)
- Xueqing Yang
- Yu Fan
- Feng Xiao (ORCID: https://orcid.org/0009-0009-2680-609X)
- Lijuan Jiang (ORCID: https://orcid.org/0000-0003-2654-7920)
- Liqin Zhao (ORCID: https://orcid.org/0000-0003-4901-7471)
- Shu-Yi Ye
Institutions
- Union Hospital (HK)
- National Health and Family Planning Commission (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1186/s12964-025-02159-2
- Citations
- 3
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Natural Science Foundation of China