ADAPTIVE IMMUNE SYSTEM OF MALNUTRITION CHILDREN IN TEGALWANGI VILLAGE, CIREBON REGENCY

Malnutrition consisting of poor nutrition, stunting, and undernutrition is one of the most common health problems in Indonesia. Based on data on the number of malnourished toddlers in Cirebon district, Weru sub-district has a relatively high number, including 208 toddlers with malnutrition, 164 thin toddlers and 281 short toddlers. To determine the adaptive immune system as reviewed from the CD4+ and IgM levels of malnourished children in Tegalwangi Village, Weru District, Cirebon Regency. This type of research is observational research. By using 50 malnourished children as samples in this study. Measurement of CD4+ and IgM levels uses the Elisa (enzyme-linked immunosorbent assay) method. The data analysis technique used is the Chi Square test. From 50 samples of malnourished children in Tegalwangi Village, Weru District, Cirebon Regency, the results obtained were children at risk of low CD4+ levels were boys (OR=0.508, p value>0.05), children aged 42-60 months (OR=1.969, p value>0.05), children with short categories (OR=2.857, p value>0.05) and malnourished children (OR=2.000, p value>0.05). Children at risk of low IgM levels are boys (OR=0.692, p value>0.05), children aged 42-60 months (OR=1.444, p value>0.05), children in the short category (OR=2.550, p value>0.05) and malnourished children (OR=1.385, p value>0.05). It can be concluded that the adaptive immune system of malnourished children in Tegalwangi Village, Weru District, Cirebon Regency is not significant.