What single-cell RNA sequencing taught us about <i>MGMT</i> expression in glioblastoma

Single-cell data suggest that <i>MGMT</i> expression falls on a continuous spectrum. A smaller percentage of tumor cells express <i>MGMT</i> when <i>MGMT</i>p is methylated.

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Publication Details

Journal
Neuro-Oncology Advances
Published
2025-01-01
DOI
https://doi.org/10.1093/noajnl/vdaf058
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

What single-cell RNA sequencing taught us about MGMT expression in glioblastoma

Wenyin Shi, Iyad Alnahhas, Marium Nadeem Khan
Neuro-Oncology Advances
Glioma Diagnosis and Treatment
article

What single-cell RNA sequencing taught us about MGMT expression in glioblastoma

Wenyin Shi, Iyad Alnahhas, Marium Nadeem Khan
article en

Abstract

Single-cell data suggest that <i>MGMT</i> expression falls on a continuous spectrum. A smaller percentage of tumor cells express <i>MGMT</i> when <i>MGMT</i>p is methylated.

Neuro-Oncology AdvancesVol. 7(1)
Thomas Jefferson University (US)
Good health and well-being
Openalex Percentile: Top 92%
Glioma Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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What single-cell RNA sequencing taught us about <i>MGMT</i> expression in glioblastoma — Wenyin Shi, Iyad Alnahhas, et al. · Neuro-Oncology Advances (2025) | TGRS Research Map | TGRS