Efficacy of overnight leave-on sandwich therapy with 5% cysteamine and ectoine cream compared to hydroquinone 4% cream for treatment of melasma: a double-blind randomized controlled trial

Both treatment regimens effectively improved melasma pigmentation and QoL. Either 5% cysteamine with ectoine or 4% hydroquinone with ectoine can be considered viable treatment options for melasma.

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Publication Details

Journal
Acta Dermatovenerologica Alpina Pannonica et Adriatica
Published
2025-01-01
DOI
https://doi.org/10.15570/actaapa.2025.4
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
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article

Efficacy of overnight leave-on sandwich therapy with 5% cysteamine and ectoine cream compared to hydroquinone 4% cream for treatment of melasma: a double-blind randomized controlled trial

Alamanda Murasmita, Nurrahma Wahyu Fitriyani, Sinta Murlistyarini, Ervina Rosmarwati et al.
Acta Dermatovenerologica Alpina Pannonica et Adriatica
Dermatologic Treatments and Research
article

Efficacy of overnight leave-on sandwich therapy with 5% cysteamine and ectoine cream compared to hydroquinone 4% cream for treatment of melasma: a double-blind randomized controlled trial

Alamanda Murasmita, Nurrahma Wahyu Fitriyani, Sinta Murlistyarini, Ervina Rosmarwati, Arie Kusumawardani, Silvia Veronica Setiawan, Lilik Norawati Ashadi
article en

Abstract

Both treatment regimens effectively improved melasma pigmentation and QoL. Either 5% cysteamine with ectoine or 4% hydroquinone with ectoine can be considered viable treatment options for melasma.

Acta Dermatovenerologica Alpina Pannonica et AdriaticaVol. 34(1)
Sebelas Maret University (ID), University of Brawijaya (ID), Gatot Soebroto Army Hospital (ID)
Good health and well-being
Openalex Percentile: Top 88%
Dermatologic Treatments and Research
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Efficacy of overnight leave-on sandwich therapy with 5% cysteamine and ectoine cream compared to hydroquinone 4% cream for treatment of melasma: a double-blind randomized controlled trial — Alamanda Murasmita, Nurrahma Wahyu Fitriyani, et al. · Acta Dermatovenerologica Alpina Pannonica et Adriatica (2025) | TGRS Research Map | TGRS