Physiologically—Modeled Dynamic Stimulation and Growth Factors Induce Differentiation of Mesenchymal Stem Cells to a Vascular Endothelial Cell Phenotype
These findings suggest that the dynamic microenvironment created by perfusion, in contrast to constant frequency, combined with growth factors, enhances MSCs differentiation toward a vascular endothelial-like phenotype.
Authors
- Helena D. Zomer (ORCID: https://orcid.org/0000-0002-2092-6906)
- Peter S. McFetridge (ORCID: https://orcid.org/0000-0002-3177-8750)
- Calum McFetridge (ORCID: https://orcid.org/0000-0002-1110-1523)
- Mediha Gurel (ORCID: https://orcid.org/0000-0001-9732-5706)
- Walter L. Murfee (ORCID: https://orcid.org/0000-0002-8247-4722)
Institutions
- University of Florida (US)
- Bitlis Eren University (TR)
- Cukurova University (TR)
Publication Details
- Journal
- Microcirculation
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1111/micc.70007
- Citations
- 2
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 3.25
Funders
- American Heart Association
- National Institutes of Health